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Dr. Nagendra Mishra

M.S., DNB (Urology)

Senior Consultant Urologist 

Specialist in Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)

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He is a pioneer in diagnosing, managing and treating IC/BPS. When he was being trained in Urology in Jaslok Hospital Mumbai in 1990-91 the common thinking was that IC/BPS does not exist in India. It is a disease of western world.

Started taking interest in Interstitial Cystitis/Bladder Pain Syndrome from 1993 when he realised that the patient which he was treating as Tuberculosis was actually having some other disease. On further researching he found that the patient was suffering from  IC/BPS. This kindled his interest in IC/BPS and a new journey began for IC/BPS in India.Dr. Mishra took leadership and devoted his life to help IC/BPS patients.He established the one and only Interstitial cystitis bladder pain center in India at Ahmedabad.

He is pioneer in spreading the message that IC/BPS  does exist in India and is not uncommon.  He contacted Interstitial Cystitis Association(USA) and expressed interest in the disease. He was invited to attend IC/BPS meeting in Washington DC in 1997 as an international speaker. This meeting was hosted by ICA and NIH(National Institute of Health)USA.  He presented papers in local, national and international meetings, organised symposium on IC/BPS at many places and has many international publications to his credit. He has written a book on IC/BPS and also written a chapter on IC/BPS in a urogynaecology book.His name is synonyms with IC/BPS in INDIA. He was also invited to USA, Europe and Japan multiple times as international speaker where he put forth his view, concept and understanding of IC/BPS in front of whole world.

Visiting Consultant 

Aartham Multi Super Speciality Hospital

Ambavadi, Ahmedabad

Empire hospital

Sola Raod, S.G.Highway, Ahmedabad

Health 1 Super Speciality Hospital

Shilaj, Ahmedabad 

Interstitial cystitis center in Ahmedabad is tertiary referral center for IC/BPS patients and has treated maximum number of patients in India. Patients from all over India are referred for diagnosis and treatment.We have record of our patients from 2000.

We treat patients with empathy. We believe in multimodal therapy and believe in treating patients at our center without referring them to other specialist. We believe that bladder imflammation is the primary abnormality and if you treat bladder all other secondary conditions  will also improve. Because the etiopathology is not known we believe in multimodal therapy and have achieved best results in the world with our  treatment protocol.

We offer  reconstructive surgical therapy to our patients who do not improve after cystoscopy therapeutic hydrodistension and  adequate oral and intravesical agents. Botox is not a preferred modality of treatment as the results are not good.

Publications

Role of patch cystoplasty in intractable interstitial cystitis/bladder pain syndrome

Mishra, Nagendra Nath

Buford K, Peters KM, Riedl C, Mishra NN, Jacques WJ, Lovász S, Pinto RA, Birder L. Global Consensus on Interstitial Cystitis/Bladder Pain Syndrome: An Update on Therapeutic Treatments. Neurourol Urodyn. 2025 Aug 10.

Doi: 10.1002/nau.70106. PMID: 40783827.

Mishra N N.Interstitial Cystitis/Bladder Pain Syndreome(IC/BPS): Single Center 20 year experience and treatment results in India.Neurourol Urodyn.2022;41:1390-1398

Intravesical Tacrolimus dissolved in water is absorbed through bladder mucosa in Interstitial Cystitis /Bladder Pain Syndrome(IC/BPS):Journal of Urology 2019 Vol. 201, No. 4S, Supplement: Abstract poster e691 

Clinical presentation and treatment of Bladder Pain Syndrome/Interstitial Cystitis in India:Review  article  Transl Androl Urol 2015;4(5):512-523  

Interstitial Cystitis/Painful Bladder Syndrome(IC/PBS) Dilemmas in Diagnosis and treatment: Nagendra Mishra, Current Women’s Health Reviews, 2013,9,122-130 

“Interstitial cystitis/painful bladder syndrome and associated medical conditions with an emphasis on irritable bowel syndrome, fibromyalgia and chronic fatigue syndrome”. Nickel JC, Tripp D, Pontari M, Moldwin R, Mayer R, Carr LK, Doggweiler R, Claire Yang, Mishra N, Nordling J . Journal of Urology 2010-04;184:1358-1363

“International survey on interstitial cystitis”. Mishra N,  Meijlink J. International journal of urology 2003;10supl: s59-s60 

Mishra N.N: Patch cystoplasty in Intractable IC/BPS: Paper accepted for publication in Urology Annals in May 2025

Nagendra Mishra: Hunners lesion(HL) diagnosis in initial workup of Interstitial Cystitis/Bladder Pain Syndrome is mandatory for managing the patients:Journal of Urology2020 Vol.203,No.4s,Supplement:Abstract poster e96

The Urological Society of India survey on urinary incontinence practice patterns among urologists:Indian Journal of Urology;2018,34(3):202-11 

Bladder pain syndrome /Interstitial Cystitis(BPS/IC) . Chapter written in Urogynecology and Pelvic Reconstructive Surgery:Jaypee Publication,130-142. 2016 

Authored  a book “Interstitial Cystitis in 2010:Not yet tamed” which was published in Feb 2010 at Indian Urology Society Annual Meeting  at Agra India in 2010 

“Psychosocial Phenotyping of Women with IC/PBS:A Case Contro Study”. Nickel JC, Tripp D, Pontari M, Moldwin R, Mayer R, Carr LK, Doggweiler R, Claire Yang, Mishra N, Nordling J . Journal of Urology 2010-02;183:167-172 

Mishra N. Are glomerulations typical of interstitial cystitis? AUA 2000; Abstr Poster 270. 

Mishra N.N.Why Augmentation Cystoplasty Alone works in Intractable Interstitial Cystitis /Bladder Pain Syndrome(IC/BPS)?. Journal of Urology.2023; Vol. 209, No. 4S, Supplement:e154

Nagendra N Mishra et. al:Intravesical tacrolimus in treatment of intractable interstitial cystitis/bladder pain syndrome–A pilot study: International Journal of Urology (2019)26(Suppl. 1), 68–72

Intravesical Tacrolimus in Treatment of Bladder Pain Syndrome/Interstitial Cystitis: Journal of Urology. 2016,195(4):e317–e318 

Clinical and Psychological Parameters associated with Pain Pattern Phenotypes in 

Women with Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS): Jour of Uro.2015-01,193:139-144 

Mapping of Pain Phenotypes in Female Patients with Bladder Pain Syndrome/Interstitial Cystitis and Controls: Nickel JC, Tripp D, Pontari M, Moldwin R, Mayer R, Carr LK, Doggweiler R, Claire Yang, Mishra N, Nordling J Eur Urol 2012; 62:1188-1194 

Childhood sexual trauma in women with interstitial cystitis/bladderpain syndrome: a case control study. Nickel JC, Tripp D, Pontari M, Moldwin R, Mayer R,  Claire Yang, Mishra N, Nordling J .Canadian Urology Association Journal   CUAJ 2011; 5: 410-415

“Primary evaluation of patients suspected of having IC”. Nordling J, Anjum FH, Bade JJ,Mishra N et al. Eur Urol 2004;45:662-669 

Articles

  • “Interstitial Cystitis in India- A simple Practical Approach ” Article published special supplement on  2ND International Consultation on Interstitial Cystitis , Japan, march 2007. (22-27)
  • IC in 2004 – Need for clarification” article published in European Urology Today (official news magazine of European Urology Association – Dec 2003)
  • Many articles in magazines to increase awareness about interstitial cystitis.

Special Achievements

  • Invited to attend International Consensus Meeting on IC/BPS which was held in North Carolina USA in April 2025. In this meeting invited experts on IC/BPS from all over the world came to consensus on few aspects of IC/BPS
  • Delivered a lecture on “Bladder Strain Hypothesis as a etiology for IC/BPS”
  • At Kyoto Japan at 5th International Consultations Interstitial Cystitis Japan. In August 2024.
  • Conducted symposium on IC/BPS in USICON 2024 held at Patna in Feb 2024.
  • Have delivered lectures at many places in India and abroad on Interstitial cystitis to raise awareness about this neglected disease.
  • Delivered a lecture on ‘Surgical and Non Surgical management of IC/BPS’ at Istanbul in Oct 2023 during SIU(International  Urology Surgeons Association) 2023 annual conference.
  • Was invited to speak on ‘Surgical approaches in end stage IC/BPS’ at New York in July 2023 during ESSIC(International Society for Study of Interstitial Cystitis) annual conference 2023.
  • Was invited to speak on IC/BPS at Calcutta in Jan 2023 during FOGSI 2023 annual meeting(Federation of Obstetric and Gynaecological Societies of India).
  • Organising committee member of International Inerstitial cystitis meeting held in New Delhi in Nov. 2016
  • Running Interstitial Cystitis center in India and have treated maximum number of Interstitial cystitis patients in India. The center is a tertiary referral centre for Painful bladder patient in India.
  • Founder of International painful bladder foundation which is a registered organisation based in Netherland
  • International expert at European Society for Study of Interstitial Cystitis (ESSIC) meeting held at Philaedelphia, USA in June 2014
  • Invited as International expert at 3rd ICICJ( INTERNATIONAL CONSULTATION ON INTERSTITIAL CYSTITIS JAPAN) at Kyoto , JAPAN in Mar. 2013
  • Chaired the symposium on PAINFUL BLADDER SYNDROME in USICON 2013which was held at PUNE in Jan 2013.
  • Chaired the symposium on PAINFUL BLADDER SYNDROME in USICON 2010 which was held at AGRA in February 2010
  • Founder chairman Indian interstitial cystitis /painful bladder syndrome(IC/PBS) society. Major contribution in framing Indian IC/PBS guidelines.
  • Invited as international expert at interstitial cystitis definition meeting held at Miami in Feb. 2008. This definition was later adopted in AUA BPS/IC
  • International expert committee member NIH/ NIDDK meeting on MAPP(Multiple approach to pelvic pain) held at BALTIMORE , MARYLAND 
  • Attended the IAPO(International Association of Patients Organizations) meeting on public health and intellectual property rights at GENEVA in Nov. 2007
  • International expert at 2nd ICICJ( INTERNATIONAL CONSULTATION ON INTERSTITIAL CYSTITIS JAPAN) at Kyoto , JAPAN in Mar. 2007
  • Chaired the symposium on PAINFUL BLADDER SYNDROME in USICON 2007 which was held at PATNA on 8th February 2007
  • International expert at European Society for Study of Interstitial Cystitis (ESSIC), held at Copenhagen, Denmark in June 2004
  • International expert at European Society for Study of Interstitial Cystitis (ESSIC), held at Copenhagen, Denmark in May 2003 and was member of committee which framed guidelines for cystoscopic classification of interstitial cystitis
  • International expert at first INTERNATIONAL CONSULTATION ON INTERSTITIAL CYSTITIS JAPAN at Kyoto , JAPAN in Mar.2003
  • Awarded grant to study  the effect  of Hydrodistension  on  urinary  bladder mucosa  by  NIDDK/ICA, New York, USA in 1999

International Presentations

  • Intravesical Tacrolimus in Interstitial Cystitis- poster accepted at American Urological Association annual meeting to be held at San Diego in May 2016
  • “Intravesical Tacrolimus in Interstitial Cystitis- Pilot Study” at International Interstitial Society Meeting at  Philedelphia in June 2014
  • “Interstitial Cystitis-Long term results” at International Interstitial Society Meeting at  Philedelphia in June 2014
  • “Simple diagnostic approach to complex problem painful bladder syndrome”- 2006 International Symposium: Frontiers in painful bladder syndrome and interstitial cystitis held at USA, October 2006
  • “International survey on interstitial cystitis”, American Urological Association meeting at Chicago, April 2003 
  • three papers at the “International Symposium on IC and Bladder Research”, Minneapolis, MN, October 2000.

        1.“Interstitial Cystitis in India – Lessons”,

        2.“Effect of Hydro-distention on bladder mucosa and sub-mucosa”,

        3.“Are glomerulations present in patients of other diseases?”

  • “Are glomerulations typical of Interstitial Cystitis?” at American Urology Association 2000 annual meeting, Atlanta, GA
  • “Ultrasound diagnosis of Interstitial Cystitis” at International Symposium on Interstitial Cystitis in Washington DC, October 1997

Clinical Activity at Center

Clinical Activity
@
Center

We consulted the following number of patients (male and female both) in particular mentioned year.

Sr. No. Year Female Male Total
02
2002
13
05
18
03
2003
14
06
20
04
2004
11
06
17
05
2005
04
05
09
06
2006
07
09
16
07
2007
16
13
29
08
2008
16
10
26
09
2009
19
13
32
10
2010
12
07
19
11
2011
07
06
13
12
2012
13
07
20
13
2013
08
07
15
14
2014
08
03
11
15
2015
08
04
12
16
2016
09
10
19
17
2017
16
06
22
18
2018
17
08
25
19
2019
20
24
44
20
2020
03
02
05
21
2021
16
12
28
22
2022
13
12
25
23
2023
11
32
43
24
2024
15
07
22
25
2025
08
14
22

294

226

520

Clinical work at center

IMG-20250921-WA0034
IMG-20250921-WA0037
IMG-20250921-WA0044
IMG-20250921-WA0061
IMG-20250921-WA0066
IMG-20250921-WA0067
IMG-20250921-WA0069